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In Silico Mechanistic Profiling to Probe Small Molecule Binding to Sulfotransferases

Drug metabolizing enzymes play a key role in the metabolism, elimination and detoxification of xenobiotics, drugs and endogenous molecules. While their principal role is to detoxify organisms by modifying compounds, such as pollutants or drugs, for a rapid excretion, in some cases they render their...

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書誌詳細
主要な著者: Martiny, Virginie Y., Carbonell, Pablo, Lagorce, David, Villoutreix, Bruno O., Moroy, Gautier, Miteva, Maria A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765257/
https://ncbi.nlm.nih.gov/pubmed/24039991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073587
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