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In Silico Mechanistic Profiling to Probe Small Molecule Binding to Sulfotransferases

Drug metabolizing enzymes play a key role in the metabolism, elimination and detoxification of xenobiotics, drugs and endogenous molecules. While their principal role is to detoxify organisms by modifying compounds, such as pollutants or drugs, for a rapid excretion, in some cases they render their...

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Detalhes bibliográficos
Main Authors: Martiny, Virginie Y., Carbonell, Pablo, Lagorce, David, Villoutreix, Bruno O., Moroy, Gautier, Miteva, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765257/
https://ncbi.nlm.nih.gov/pubmed/24039991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073587
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