Glycan Elongation Beyond the Mucin Associated Tn Antigen Protects Tumor Cells from Immune-Mediated Killing

Membrane bound mucins are up-regulated and aberrantly glycosylated during malignant transformation in many cancer cells. This results in a negatively charged glycoprotein coat which may protect cancer cells from immune surveillance. However, only limited data have so far demonstrated the critical st...

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Bibliografske podrobnosti
Main Authors: Madsen, Caroline B., Lavrsen, Kirstine, Steentoft, Catharina, Vester-Christensen, Malene B., Clausen, Henrik, Wandall, Hans H., Pedersen, Anders Elm
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765166/
https://ncbi.nlm.nih.gov/pubmed/24039759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072413
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