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Cancer Associated Aberrant Protein O-Glycosylation Can Modify Antigen Processing and Immune Response

Aberrant glycosylation of mucins and other extracellular proteins is an important event in carcinogenesis and the resulting cancer associated glycans have been suggested as targets in cancer immunotherapy. We assessed the role of O-linked GalNAc glycosylation on antigen uptake, processing, and prese...

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Detalhes bibliográficos
Main Authors: Madsen, Caroline B., Petersen, Cecilie, Lavrsen, Kirstine, Harndahl, Mikkel, Buus, Søren, Clausen, Henrik, Pedersen, Anders E., Wandall, Hans H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506546/
https://ncbi.nlm.nih.gov/pubmed/23189185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050139
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