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Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM-1

Bv8 (prokineticin 2) expressed by Gr1(+)CD11b(+) myeloid cells is critical for VEGF-independent tumor angiogenesis. Although G-CSF has been shown to be a key inducer of Bv8 expression, the basis for Bv8 production in driving tumor angiogenesis is undefined. Since the cell adhesion molecule CEACAM1 t...

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Bibliografische gegevens
Hoofdauteurs: Lu, Rongze, Kujawski, Maciej, Pan, Hao, Shively, John E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765079/
https://ncbi.nlm.nih.gov/pubmed/22406619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3016
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