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Effects of epigallocatechin gallate, L-ascorbic acid, α-tocopherol and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation
Oxidation of polyunsaturated fatty acids (PUFAs) releases α, β-unsaturated aldehydes that modify deoxyguanosine (dG) to form cyclic 1,N(2)-propanodeoxyguanosine adducts. One of the major adducts detected in vivo is acrolein-derived 1,N(2)-propanodeoxyguanosine (Acr-dG). We used a chemical model syst...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764924/ https://ncbi.nlm.nih.gov/pubmed/20574923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635580903532424 |
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