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A3 Domain Region 1803–1818 Contributes to the Stability of Activated Factor VIII and Includes a Binding Site for Activated Factor IX

A recent chemical footprinting study in our laboratory suggested that region 1803–1818 might contribute to A2 domain retention in activated factor VIII (FVIIIa). This site has also been implicated to interact with activated factor IX (FIXa). Asn-1810 further comprises an N-linked glycan, which seems...

詳細記述

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書誌詳細
主要な著者: Bloem, Esther, Meems, Henriet, van den Biggelaar, Maartje, Mertens, Koen, Meijer, Alexander B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764813/
https://ncbi.nlm.nih.gov/pubmed/23884417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500884
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