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Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking
Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood outgrowth endothelial cells, even when factor VI...
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| Publicat a: | Haematologica |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ferrata Storti Foundation
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395109/ https://ncbi.nlm.nih.gov/pubmed/28057741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.153163 |
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