Heparin Dodecasaccharide Containing Two Antithrombin-binding Pentasaccharides: STRUCTURAL FEATURES AND BIOLOGICAL PROPERTIES

The antithrombin (AT) binding properties of heparin and low molecular weight heparins are strongly associated to the presence of the pentasaccharide sequence AGA*IA (A(NAc,6S)-GlcUA-A(NS,3,6S)-I(2S)-A(NS,6S)). By using the highly chemoselective depolymerization to prepare new ultra low molecular wei...

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Detalhes bibliográficos
Main Authors: Viskov, Christian, Elli, Stefano, Urso, Elena, Gaudesi, Davide, Mourier, Pierre, Herman, Frederic, Boudier, Christian, Casu, Benito, Torri, Giangiacomo, Guerrini, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764794/
https://ncbi.nlm.nih.gov/pubmed/23843463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.485268
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