Novel HLA-B27-restricted Epitopes from Chlamydia trachomatis Generated upon Endogenous Processing of Bacterial Proteins Suggest a Role of Molecular Mimicry in Reactive Arthritis

Reactive arthritis (ReA) is an HLA-B27-associated spondyloarthropathy that is triggered by diverse bacteria, including Chlamydia trachomatis, a frequent intracellular parasite. HLA-B27-restricted T-cell responses are elicited against this bacterium in ReA patients, but their pathogenetic significanc...

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Hlavní autoři: Alvarez-Navarro, Carlos, Cragnolini, Juan J., Dos Santos, Helena G., Barnea, Eilon, Admon, Arie, Morreale, Antonio, López de Castro, José A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764788/
https://ncbi.nlm.nih.gov/pubmed/23867464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493247
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