The apoptotic effects of sirtuin1 inhibitor on the MCF-7 and MRC-5 cell lines

Sirtuin1 (SIRT1) is an enzyme that deacetylates histones and several nonhistone proteins including p53 during stress and plays an important role in the survival of tumor cells. Hereby, this study describes the potency of salermide as a SIRT1 inhibitor to induce apoptosis in the MCF-7 and MRC-5 cell...

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Hlavní autoři: Dastjerdi, M Nikbakht, Salahshoor, M R, Mardani, M, Rabbani, M, Hashemibeni, B, Gharagozloo, M, Kazemi, M, Esmaeil, N, Roshankhah, Sh, Golmohammadi, R, Mobarakian, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764679/
https://ncbi.nlm.nih.gov/pubmed/24019817
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