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Development and characterization of controlled release polar lipid microparticles of candesartan cilexetil by solid dispersion

Candesartan cilexetil (CC) is a newer class of angiotensin II receptor antagonist used for the treatment of hypertension. The solubility of the CC is very poor and its oral bioavailability is only 15%. The controlledrelease polar lipid microparticles of CC (formulations F1, F2, F3 and F4) were prepa...

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Hlavní autoři: Kamalakkannan, V, Puratchikody, A, Ramanathan, L
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764676/
https://ncbi.nlm.nih.gov/pubmed/24019822
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