Parasite antigen-specific, IL-4-, TGFβ- and IL-1- dependent expansion of Th9 cells is associated with clinical pathology in human lymphatic filariasis

Th9 cells are a subset of CD4(+) T cells, shown to be important in allergy, autoimmunity and anti-tumor responses. However, their role in human infectious diseases has not been explored in detail. We identified a population of IL-9 and IL-10 co-expressing cells (lacking IL-4 expression) in normal in...

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Autores principales: Anuradha, Rajamanickam, George, Parakkal Jovvian, Hanna, Luke E., Chandrasekaran, Vedachalam, Kumaran, Paul, Nutman, Thomas B., Babu, Subash
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764459/
https://ncbi.nlm.nih.gov/pubmed/23913964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300911
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