Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan-1

BACKGROUND: We have recently demonstrated that injured patients in hemorrhagic shock shed syndecan-1 and that the early use of fresh frozen plasma (FFP) in these patients is correlated with improved clinical outcomes. As the lungs are frequently injured after trauma, we hypothesized that hemorrhagic...

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Hauptverfasser: Peng, Zhanglong, Pati, Shibani, Potter, Daniel, Brown, Ryan, Holcomb, John B, Grill, Raymond, Wataha, Kathryn, Park, Pyong Woo, Xue, Hasen, Kozar, Rosemary A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764452/
https://ncbi.nlm.nih.gov/pubmed/23807246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31829f91fc
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