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Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan-1

BACKGROUND: We have recently demonstrated that injured patients in hemorrhagic shock shed syndecan-1 and that the early use of fresh frozen plasma (FFP) in these patients is correlated with improved clinical outcomes. As the lungs are frequently injured after trauma, we hypothesized that hemorrhagic...

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Detalhes bibliográficos
Main Authors: Peng, Zhanglong, Pati, Shibani, Potter, Daniel, Brown, Ryan, Holcomb, John B, Grill, Raymond, Wataha, Kathryn, Park, Pyong Woo, Xue, Hasen, Kozar, Rosemary A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764452/
https://ncbi.nlm.nih.gov/pubmed/23807246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31829f91fc
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