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High-resolution Structural and Thermodynamic Analysis of Extreme Stabilization of Human Procarboxypeptidase by Computational Protein Design

Recent efforts to design de novo or redesign the sequence and structure of proteins using computational techniques have met with significant success. Most, if not all, of these computational methodologies attempt to model atomic-level interactions, and hence high-resolution structural characterizati...

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Detalhes bibliográficos
Main Authors: Dantas, Gautam, Corrent, Colin, Reichow, Steve L., Havranek, James J., Eletr, Ziad M., Isern, Nancy G., Kuhlman, Brian, Varani, Gabriele, Merritt, Ethan A., Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764424/
https://ncbi.nlm.nih.gov/pubmed/17196978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.080
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