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Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators

Genome sequencing of bacterial pathogens has advanced our understanding of their evolution, epidemiology, and response to antibiotic therapy. However, we still have only a limited knowledge of the molecular changes in in vivo evolving bacterial populations in relation to long-term, chronic infection...

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Autori principali: Marvig, Rasmus Lykke, Johansen, Helle Krogh, Molin, Søren, Jelsbak, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764201/
https://ncbi.nlm.nih.gov/pubmed/24039595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003741
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