Genetic and Anatomical Basis of the Barrier Separating Wakefulness and Anesthetic-Induced Unresponsiveness

A robust, bistable switch regulates the fluctuations between wakefulness and natural sleep as well as those between wakefulness and anesthetic-induced unresponsiveness. We previously provided experimental evidence for the existence of a behavioral barrier to transitions between these states of arous...

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Detalhes bibliográficos
Main Authors: Joiner, William J., Friedman, Eliot B., Hung, Hsiao-Tung, Koh, Kyunghee, Sowcik, Mallory, Sehgal, Amita, Kelz, Max B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764144/
https://ncbi.nlm.nih.gov/pubmed/24039590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003605
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