IDENTIFICATION AND CHARACTERIZATION OF NOVEL AML1-ETO FUSION TRANSCRIPTS IN PEDIATRIC t(8;21) ACUTE MYELOID LEUKEMIA: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

t(8;21)(q22;q22) results in the AML1-ETO (A1E) fusion gene and is a common cytogenetic abnormality in acute myeloid leukemia (AML). Although insertions at the breakpoint region of the A1E fusion transcripts have been reported, additional structural alterations are largely uncharacterized. By RT-PCR...

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Detalhes bibliográficos
Main Authors: LaFiura, Katherine M., Edwards, Holly, Taub, Jeffrey W., Matherly, Larry H., Fontana, Joseph A., Mohamed, Anwar N., Ravindranath, Yaddanapudi, Ge, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763903/
https://ncbi.nlm.nih.gov/pubmed/18469864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.134
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