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Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA

Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally ch...

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Библиографические подробности
Главные авторы: Iyer, Lakshminarayan M., Zhang, Dapeng, Maxwell Burroughs, A., Aravind, L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763556/
https://ncbi.nlm.nih.gov/pubmed/23814188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt573
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