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Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA

Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally ch...

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Detalhes bibliográficos
Main Authors: Iyer, Lakshminarayan M., Zhang, Dapeng, Maxwell Burroughs, A., Aravind, L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763556/
https://ncbi.nlm.nih.gov/pubmed/23814188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt573
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