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DNA double-strand–break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

Although the DNA double-strand break (DSB) is defined as a rupture in the double-stranded DNA molecule that can occur without chemical modification in any of the constituent building blocks, it is recognized that this form is restricted to enzyme-induced DSBs. DSBs generated by physical or chemical...

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Detalhes bibliográficos
Main Authors: Schipler, Agnes, Iliakis, George
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763544/
https://ncbi.nlm.nih.gov/pubmed/23804754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt556
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