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Conservation of mRNA secondary structures may filter out mutations in Escherichia coli evolution

Recent reports indicate that mutations in viral genomes tend to preserve RNA secondary structure, and those mutations that disrupt secondary structural elements may reduce gene expression levels, thereby serving as a functional knockout. In this article, we explore the conservation of secondary stru...

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Hlavní autoři: Chursov, Andrey, Frishman, Dmitrij, Shneider, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763529/
https://ncbi.nlm.nih.gov/pubmed/23783573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt507
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