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Conservation of mRNA secondary structures may filter out mutations in Escherichia coli evolution

Recent reports indicate that mutations in viral genomes tend to preserve RNA secondary structure, and those mutations that disrupt secondary structural elements may reduce gene expression levels, thereby serving as a functional knockout. In this article, we explore the conservation of secondary stru...

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Detalhes bibliográficos
Main Authors: Chursov, Andrey, Frishman, Dmitrij, Shneider, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763529/
https://ncbi.nlm.nih.gov/pubmed/23783573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt507
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