Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells

We previously reported that marchantin M (Mar) is an active agent to induce apoptosis in human prostate cancer (PCa), but the molecular mechanisms of action remain largely unknown. Here, we demonstrate that Mar potently inhibited chymotrypsin-like and peptidyl-glutamyl peptide-hydrolyzing activities...

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Main Authors: Jiang, H, Sun, J, Xu, Q, Liu, Y, Wei, J, Young, C Y F, Yuan, H, Lou, H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763447/
https://ncbi.nlm.nih.gov/pubmed/23928700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.285
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