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A Novel Therapeutic Strategy for the Treatment of Glioma, Combining Chemical and Molecular Targeting of Hsp90α

Hsp90α's vital role in tumour survival and progression, together with its highly inducible expression profile in gliomas and its absence in normal tissue and cell lines validates it as a therapeutic target for glioma. Hsp90α was downregulated using the post-transcriptional RNAi strategy (sihsp9...

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מידע ביבליוגרפי
Main Authors: Mehta, Adi, Shervington, Leroy, Munje, Chinmay, Shervington, Amal
פורמט: Artigo
שפה:Inglês
יצא לאור: Molecular Diversity Preservation International (MDPI) 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763420/
https://ncbi.nlm.nih.gov/pubmed/24213135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3044228
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