Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity

Previous studies have demonstrated that p210 BCR/ABL1 interacts directly with the xeroderma pigmentosum group B (XPB) protein, and that XPB is phosphorylated on tyrosine in cells that express p210 BCR/ABL1. In the current study, we have constructed a p210 BCR/ABL1 mutant that can no longer bind to X...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pannucci, N L, Li, D, Sahay, S, Thomas, E K, Chen, R, Tala, I, Hu, T, Ciccarelli, B T, Megjugorac, N J, Adams III, H C, Rodriguez, P L, Fitzpatrick, E R, Lagunoff, D, Williams, D A, Whitehead, I P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763389/
https://ncbi.nlm.nih.gov/pubmed/23955590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.36
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