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Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression
As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify the Cdk1 substrate, Ect2, as a central regulator of mitotic rounding, thus uncovering a link between the cell-cycle machinery that drives mitotic entry and its accompanying actin r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763371/ https://ncbi.nlm.nih.gov/pubmed/22898780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.06.003 |
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