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Dose Responsiveness and Variation Among Inbred Strains of Mice in Production of Interferon After Treatment with Poly (I)· Poly (C) [Poly-d-Lysine] Complexes

Poly-d-lysine forms a stochiometric complex with poly(I) · poly(C) which has a higher T(m) (83 C in 0.15 m NaCl) than the uncomplexed double-stranded polyribo-nucleotide (63 C). The complex was superior to poly(I) · poly(C) alone as an interferon inducer in vivo. Significant serum interferon titers...

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Detalhes bibliográficos
Main Authors: Rice, J. M., Turner, W., Chirigos, M. A., Spahn, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC376318/
https://ncbi.nlm.nih.gov/pubmed/4330315
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