Dose Responsiveness and Variation Among Inbred Strains of Mice in Production of Interferon After Treatment with Poly (I)· Poly (C) [Poly-d-Lysine] Complexes

Poly-d-lysine forms a stochiometric complex with poly(I) · poly(C) which has a higher T(m) (83 C in 0.15 m NaCl) than the uncomplexed double-stranded polyribo-nucleotide (63 C). The complex was superior to poly(I) · poly(C) alone as an interferon inducer in vivo. Significant serum interferon titers...

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Bibliografische Detailangaben

Veröffentlicht in:	Appl Microbiol
Hauptverfasser:	Rice, J. M., Turner, W., Chirigos, M. A., Spahn, G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1971
Schlagworte:	Clinical Microbiology, Virology, and Immunology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC376318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4330315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.22.3.380-386.1971
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