Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression

Short-term starvation (STS) protects normal cells while simultaneously sensitizing malignant cells to high-dose chemotherapeutic drugs in mice and possibly patients. The fasting-dependent protection of normal cells and sensitization of malignant cells depends, in part, on reduced levels of insulin-l...

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Bibliographic Details
Main Authors: Brandhorst, Sebastian, Wei, Min, Hwang, Saewon, Morgan, Todd E., Longo, Valter D.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762887/
https://ncbi.nlm.nih.gov/pubmed/23454633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.02.016
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