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Three-Dimensional Quantification of Cellular Traction Forces and Mechanosensing of Thin Substrata by Fourier Traction Force Microscopy

We introduce a novel three-dimensional (3D) traction force microscopy (TFM) method motivated by the recent discovery that cells adhering on plane surfaces exert both in-plane and out-of-plane traction stresses. We measure the 3D deformation of the substratum on a thin layer near its surface, and inp...

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Detalhes bibliográficos
Main Authors: del Álamo, Juan C., Meili, Ruedi, Álvarez-González, Begoña, Alonso-Latorre, Baldomero, Bastounis, Effie, Firtel, Richard, Lasheras, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762859/
https://ncbi.nlm.nih.gov/pubmed/24023712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069850
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