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The SCAR/WAVE complex is necessary for proper regulation of traction stresses during amoeboid motility

Cell migration requires a tightly regulated, spatiotemporal coordination of underlying biochemical pathways. Crucial to cell migration is SCAR/WAVE–mediated dendritic F-actin polymerization at the cell's leading edge. Our goal is to understand the role the SCAR/WAVE complex plays in the mechani...

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Библиографические подробности
Главные авторы: Bastounis, Effie, Meili, Ruedi, Alonso-Latorre, Baldomero, del Álamo, Juan C., Lasheras, Juan C., Firtel, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204062/
https://ncbi.nlm.nih.gov/pubmed/21900496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0278
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