Generation and Characterization of a Diabody Targeting the α(v)β(6) Integrin

The α(v)β(6) integrin is up-regulated in cancer and wound healing but it is not generally expressed in healthy adult tissue. There is increasing evidence that it has a role in cancer progression and will be a useful target for antibody-directed cancer therapies. We report a novel recombinant diabody...

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Detalhes bibliográficos
Main Authors: Kogelberg, Heide, Miranda, Enrique, Burnet, Jerome, Ellison, David, Tolner, Berend, Foster, Julie, Picón, Carmen, Thomas, Gareth J., Meyer, Tim, Marshall, John F., Mather, Stephen J., Chester, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762766/
https://ncbi.nlm.nih.gov/pubmed/24023846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073260
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