Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 sequence associated with hepatitis-induced pathogenesis

Current diagnostic approaches that characterize T-cell deficiency by analyzing diversity of T-cell receptor sequences effectuate limited informational gain about the actual restrictiveness. For deeper insight into T-cell receptor repertoires we developed next-generation-sequencing-spectratyping, whi...

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Main Authors: Krell, Pina F. I., Reuther, Susanne, Fischer, Ute, Keller, Thomas, Weber, Stephan, Gombert, Michael, Schuster, Friedhelm R., Asang, Corinna, Stepensky, Polina, Strahm, Brigitte, Meisel, Roland, Stoye, Jens, Borkhardt, Arndt
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762095/
https://ncbi.nlm.nih.gov/pubmed/23716544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.069708
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