Improved Assessment of T-Cell Receptor (TCR) VB Repertoire in Clinical Specimens: Combination of TCR-CDR3 Spectratyping with Flow Cytometry-Based TCR VB Frequency Analysis

Antigen-specific T-cell responses may be described by combining three categories: (i) the specificity and effector functions of a T-cell population, (ii) the quantity of T-cell responses (i.e., the number of responding T cells within the CD4/CD8 population), and (iii) the “quality” of T cells (defin...

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Detalhes bibliográficos
Main Authors: Pilch, H., Höhn, H., Freitag, K., Neukirch, C., Necker, A., Haddad, P., Tanner, B., Knapstein, P. G., Maeurer, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cellular Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC119929/
https://ncbi.nlm.nih.gov/pubmed/11874861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.2.257-266.2002
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