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Impaired β-cell sensitivity to glucose and maximal insulin secretory capacity in adolescents with type 2 diabetes

BACKGROUND: Adults with type 2 diabetes mellitus (T2DM) have broad impairments in β-cell function, including severe attenuation of the first-phase insulin response to glucose, and reduced β-cell mass. In adolescents with T2DM, there is some evidence that β-cell dysfunction may be less severe. Our ob...

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Autori principali: Elder, Deborah A., Woo, Jessica G., D’Alessio, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761801/
https://ncbi.nlm.nih.gov/pubmed/19961550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-5448.2009.00601.x
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