Human circulating influenza-CD4(+) ICOS1(+)IL-21(+) T cells expand after vaccination, exert helper function, and predict antibody responses

Protection against influenza is mediated by neutralizing antibodies, and their induction at high and sustained titers is key for successful vaccination. Optimal B cells activation requires delivery of help from CD4(+) T lymphocytes. In lymph nodes and tonsils, T-follicular helper cells have been ide...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spensieri, Fabiana, Borgogni, Erica, Zedda, Luisanna, Bardelli, Monia, Buricchi, Francesca, Volpini, Gianfranco, Fragapane, Elena, Tavarini, Simona, Finco, Oretta, Rappuoli, Rino, Del Giudice, Giuseppe, Galli, Grazia, Castellino, Flora
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761599/
https://ncbi.nlm.nih.gov/pubmed/23940329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311998110
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