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Fast Matching of Transcription Factor Motifs Using Generalized Position Weight Matrix Models

The problem of finding the locations in DNA sequences that match a given motif describing the binding specificities of a transcription factor (TF) has many applications in computational biology. This problem has been extensively studied when the position weight matrix (PWM) model is used to represen...

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Detalhes bibliográficos
Main Authors: Giaquinta, Emanuele, Grabowski, Szymon, Ukkonen, Esko
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761436/
https://ncbi.nlm.nih.gov/pubmed/23919388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0289
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