ADP-Ribosylation Factor 6 Regulates Tumorigenic and Invasive Properties In vivo

This study shows that the small GTP-binding protein ADP-ribosylation factor 6 (ARF6) is an important regulator of tumor growth and metastasis. Using spontaneous melanoma tumor growth assays and experimental metastasis assays in nude mice, we show that sustained activation of ARF6 reduces tumor mass...

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Detalhes bibliográficos
Main Authors: Muralidharan-Chari, Vandhana, Hoover, Holly, Clancy, James, Schweitzer, Jill, Suckow, Mark A., Schroeder, Valerie, Castellino, Francis J., Schorey, Jeffrey S., D’Souza-Schorey, Crislyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761373/
https://ncbi.nlm.nih.gov/pubmed/19276388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1301
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