Does the combination of hyperkalemia and K(ATP) activation determine excitation rate gradient and electrical failure in the globally ischemic fibrillating heart?

Ventricular fibrillation (VF) in the globally ischemic heart is characterized by a progressive electrical depression manifested as a decline in the VF excitation rate (VFR) and loss of excitability, which occur first in the subepicardium (Epi) and spread to the subendocardium (Endo). Early electrica...

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Autores principales: Taylor, Tyson G., Venable, Paul W., Booth, Alicja, Garg, Vivek, Shibayama, Junko, Zaitsev, Alexey V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761339/
https://ncbi.nlm.nih.gov/pubmed/23873793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00184.2013
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