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Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion channels mediating cardiac excitability and conduction, but how this regulation translates to the normal and ischemic heart remains unknown. Diverging results on CaMKII regulation of Na(+) channels further prevent pr...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Heart Circ Physiol
主要な著者: Warren, Mark, Sciuto, Katie J., Taylor, Tyson G., Garg, Vivek, Torres, Natalia S., Shibayama, Junko, Spitzer, Kenneth W., Zaitsev, Alexey V.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407168/
https://ncbi.nlm.nih.gov/pubmed/28130334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2016
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