Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion channels mediating cardiac excitability and conduction, but how this regulation translates to the normal and ischemic heart remains unknown. Diverging results on CaMKII regulation of Na(+) channels further prevent pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Warren, Mark, Sciuto, Katie J., Taylor, Tyson G., Garg, Vivek, Torres, Natalia S., Shibayama, Junko, Spitzer, Kenneth W., Zaitsev, Alexey V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407168/
https://ncbi.nlm.nih.gov/pubmed/28130334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2016
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