Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion channels mediating cardiac excitability and conduction, but how this regulation translates to the normal and ischemic heart remains unknown. Diverging results on CaMKII regulation of Na(+) channels further prevent pr...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Heart Circ Physiol
Asıl Yazarlar: Warren, Mark, Sciuto, Katie J., Taylor, Tyson G., Garg, Vivek, Torres, Natalia S., Shibayama, Junko, Spitzer, Kenneth W., Zaitsev, Alexey V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407168/
https://ncbi.nlm.nih.gov/pubmed/28130334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2016
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