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Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion channels mediating cardiac excitability and conduction, but how this regulation translates to the normal and ischemic heart remains unknown. Diverging results on CaMKII regulation of Na(+) channels further prevent pr...

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書目詳細資料
發表在:Am J Physiol Heart Circ Physiol
Main Authors: Warren, Mark, Sciuto, Katie J., Taylor, Tyson G., Garg, Vivek, Torres, Natalia S., Shibayama, Junko, Spitzer, Kenneth W., Zaitsev, Alexey V.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407168/
https://ncbi.nlm.nih.gov/pubmed/28130334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2016
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