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Central endogenous angiotensin-(1–7) protects against aldosterone/NaCl-induced hypertension in female rats

In comparison to male rodents, females are protected against angiotensin (ANG) II- and aldosterone (Aldo)-induced hypertension. However, the mechanisms underlying this protective effect are not well understood. ANG-(1–7) is formed from ANG II by angiotensin-converting enzyme 2 (ACE2) and has an anti...

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Detalhes bibliográficos
Main Authors: Xue, Baojian, Zhang, Zhongming, Johnson, Ralph F., Guo, Fang, Hay, Meredith, Johnson, Alan Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761325/
https://ncbi.nlm.nih.gov/pubmed/23812385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00193.2013
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