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Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway
Hypertension is a leading cause of morbidity and mortality worldwide, and disordered sodium balance has long been implicated in its pathogenesis. Aldosterone is perhaps the key regulator of sodium balance and thus blood pressure. The sodium chloride cotransporter (NCC) in the distal convoluted tubul...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761211/ https://ncbi.nlm.nih.gov/pubmed/23739593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00053.2013 |
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