20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension

20-Hydroxyeicosatetraenoic acid (20-HETE) is a cytochrome P-450 (Cyp)-derived arachidonic acid metabolite that has been shown to increase smooth muscle contractions and proliferation, stimulate endothelial dysfunction and activation, and promote hypertension. We examined if 20-HETE contributes to mi...

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Main Authors: Ding, Yan, Wu, Cheng-Chia, Garcia, Victor, Dimitrova, Irina, Weidenhammer, Adam, Joseph, Gregory, Zhang, Frank, Manthati, Vijay L., Falck, John R., Capdevila, Jorge H., Schwartzman, Michal L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761206/
https://ncbi.nlm.nih.gov/pubmed/23825080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00292.2013
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