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Minocycline and tetracycline-class antibiotics are protective against partial seizures in vivo

INTRODUCTION: Increasing evidence suggests the role of inflammation in enhancing neuronal excitability and contributing to epileptogenesis. Tetracycline-class antibiotics minocycline, doxycycline, and tetracycline have been shown to have anti-apoptotic and anti-inflammatory effects. METHODS: We inve...

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Detalhes bibliográficos
Main Authors: Wang, Doris D., Englot, Dario J., Garcia, Paul A., Lawton, Michael T., Young, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761078/
https://ncbi.nlm.nih.gov/pubmed/22579030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2012.03.035
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