A New Approach to Control the Enigmatic Activity of Aldose Reductase

Aldose reductase (AR) is an NADPH-dependent reductase, which acts on a variety of hydrophilic as well as hydrophobic aldehydes. It is currently defined as the first enzyme in the so-called polyol pathway, in which glucose is transformed into sorbitol by AR and then to fructose by an NAD(+)-dependent...

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Autori principali: Del-Corso, Antonella, Balestri, Francesco, Di Bugno, Elisa, Moschini, Roberta, Cappiello, Mario, Sartini, Stefania, La-Motta, Concettina, Da-Settimo, Federico, Mura, Umberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760808/
https://ncbi.nlm.nih.gov/pubmed/24019949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074076
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