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A New Approach to Control the Enigmatic Activity of Aldose Reductase
Aldose reductase (AR) is an NADPH-dependent reductase, which acts on a variety of hydrophilic as well as hydrophobic aldehydes. It is currently defined as the first enzyme in the so-called polyol pathway, in which glucose is transformed into sorbitol by AR and then to fructose by an NAD(+)-dependent...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760808/ https://ncbi.nlm.nih.gov/pubmed/24019949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074076 |
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