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Human PPP1R26P1 Functions as cis-Repressive Element in Mouse Rb1
The human retinoblastoma gene (RB1) is imprinted; the mouse Rb1 gene is not. Imprinted expression of RB1 is due to differential methylation of a CpG island (CpG85), which is located in the pseudogene PPP1R26P1 in intron 2 of RB1. CpG85 serves as promoter for an alternative RB1 transcript, which is e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760807/ https://ncbi.nlm.nih.gov/pubmed/24019952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074159 |
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