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The Human Retinoblastoma Gene Is Imprinted

Genomic imprinting is an epigenetic process leading to parent-of-origin–specific DNA methylation and gene expression. To date, ∼60 imprinted human genes are known. Based on genome-wide methylation analysis of a patient with multiple imprinting defects, we have identified a differentially methylated...

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Detalhes bibliográficos
Main Authors: Kanber, Deniz, Berulava, Tea, Ammerpohl, Ole, Mitter, Diana, Richter, Julia, Siebert, Reiner, Horsthemke, Bernhard, Lohmann, Dietmar, Buiting, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791201/
https://ncbi.nlm.nih.gov/pubmed/20041224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000790
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